I tried the Latisse medication once. I applied it as directed: in an eyeliner-like way at the base of my lashes. Maybe a half hour later I had the sensation that I had done something to my lids… they felt tight. Jason came home and I said, “Do my eyes look funny?” He said, “Yeah, they look small and watery. Did you use that stuff?” And maybe it was my heightened paranoia about the side-effects (darkened lids:reversible, darkened iris: not reversible) I could swear that my lids looked tinged gray, and my cornea looked less white. Thoroughly freaked, and also forbidden by Jason to continue (“Your lashes are fine! You always look great!”, I have not used Latisse again. $120 down the toilet. However, I don’t discount the awesomeness that it could be for others. Just not for me! The photos below were taken a day later, as my eyelids were still puffy!!
The red arrows are pointing out the poofy redness that Latisse created. It is applied like an eyeliner. As you can see, that is precisely where there is swelling.